RGPV / RGTU B Pharma, PHARMACY 4th (IV) Semester PY 405 Pharmacology-I (Theory) syllabus

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Rajiv Gandhi Technological University, Bhopal (MP)
BPharma BRANCH: PHARMACY FOURTH IV SEMESTER
PY - 405 Pharmacology-I (Theory)

General Pharmacology
a.) Introduction to pharmacology, sources of drugs, dosage forms and routes of administration, mechanism of action, combined effects of drugs, factors modifying drug action, tolerance and dependence, pharmacogenetics.
b.) Absorption, distribution and excretion of drugs, principle of basic and clinical pharmacokinetics adverse drug reactions and treatment of poisoning, ADME drug interaction, bioassay of drugs and biological standardization, discovery and development of new drugs. Introduction to clinical trials.

Pharmacology of Peripheral Nervous System
a. Neurohumoral transmission (autonomous and somatic)
b. Parasympathomimetic, parasympatholytic, sympathomimetics, sympatholytics, neuron blocking agents.
c. Neuromuscular blocking agents
d. Local anaesthetic agents

Autocoids
a. Histamine, bradykinin 5- HT and their antagonists.
b. Prostaglandins, leukotrienes and platelet activating factors.

Analgesic, Antipyretic, Anti-inflammatory and Anti-Gout Drugs:
Drugs acting on Respiratory System and Pathophysiology of respiratory system:
a. Anti-asthmatic drugs including bronchodilators
b. Anti-tussives and expectorants

Books Recommended:
1. Satoskar, R.S. and Bhandarkar, S.D., Pharmacology and Pharmacotherapeutics.
2. Tripathi, K.D., Essentials of Medical Pharmcology.
3. Kulkarni, S.K., Handbook of Experimental Pharmacology, Vallabh Prakashan, New Delhi.
4. Crossland, J and Thomson, J.H., Essential of Pharmacology, Harper and Row, Publishers, New York.
5. Craig, C.R. and Stitzel, R.R., Modern Pharmacology, Little Brown and Company.
6. Rang, M.P. , Dale, M.M. and Riter, J.M., Pharmacology, Churchill Livingstone.
7. Paul, L., Principles of Pharmacology, Chamman and Hall.
8. Herfindal, E.T. and Hirschman, J.L., Clinical Pharmacy and Therapeutics, William and Wilkins.
9. Katzung, B.G., Basic and Clinical Pharmacology, Prentice Hall International.

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