RGPV / RGTU B.E. BM, 4th (IV) Semester syllabus BM 401 Biomedical Physics Revised syllabus Bio-Medical Engineering(BM)

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Rajiv Gandhi Technological University, Bhopal (MP)
B.E. (BM) Bio-Medical Engineering
401 Biomedical Physics syllabus
Revised Syllabus and Scheme of Examination Effective from July 2007

Unit-I Bioelectricity: Theory of diffusion & permeability through biological membrane, Resting Membrane potential, Generation & transmission of impulses, Ionic channels, monophasic and biphasic recordings, Electrical activity of the heart Pace maker potential, Electrocardiography. Biological transducers, Receptor potentials. Electrical activity of the brain, Hodgin- Huxley model of squid giant axon. Contemporary models of neurons Synaptic transmission.

Unit-II Elasticity of living cell materials ,Elasticity and braking strength of bones, Muscle as a helical spring, Introduction of biomaterials, Structure and properties of material used as implants: Polymer, Ceramics, Metals composite bone cements , Tissue material. Tissue responses to implant, Cellular responses to foreign soft and hard tissues, uses of implants, Viscosity of Elemental protoplasm and its determination in cell, Role of viscosity in preparation and use of Pharmaceuticals, Surface energies of living materials, Surface tension of Bio-Fluids and its measurement.

Unit-III Radiation Biophysics-Radio Emission – Law of radioactive decay half life period- Production of radioisotopes for medical use, Generation & sources of electromagnetic radiation, Interaction of radiation with matter and tissue, Useful and harmful effects of magnetic fields, Radio waves, Micro waves, Ultraviolet radiation and infrared red thickness- Photo electric, Compton and pair production process and their significance in radiology. Radiation units- Detection and measurements of radiation.

Unit-IV Fluid Biophysics System, Fluid flow across the membrane, Fick’s diffusion equation, coefficient of diffusion and permeability constant and their role in therapeutics, Influence of tubewell, Radius of tube, Length of tube and R.B.C. concentration on blood flow, Total energy equation for blood. The heart as a pump.

Unit-V Thermodynamics of living System: Living body as a thermodynamics system, Thermodynamic laws applied to bio-systems, Expressions for changes in internal energy and negative entropy change in living systems, Application of heat & mass Transfer principles to biological systems. Heat exchange, between a biological system & environment, Effect of hypothermia and hyperthermia, Production of ultra low and low temperature for medical use.

1. Biophysics; Cotteril, wiley Publisher
2. Methods in modern biophysics- Benget Notling, Springer
3. Biophysics- Pattabhi, Gautham, Kulwer Acad Publisher
4. Massey and Meredeth, “Medical Physics”.
5. David Freifelder, “Molecular Biology”, Johns and Bartlet
6. David Cooney, “Principles of Biomedical Engineering”.
7. Ruch and Patton, “Bio Physics and Medical Physiology”

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