IT 723 Bioinformatics SYLLABUS
RGTU/RGPV IT 7th sem Bioinformatics SYLLABUS
Information Technology IT 7th Semester Syllabus,
Unit I: Introduction to bioinformatics: Definition and History of Bioinformatics, Application and research of bioinformatics, finding Bioinformatics data online Bioinformatics, private and future data sources, Meta data Summary and reference systems.
Unit II: Bioinformatics Database: Characteristics and categories of Bioinformatics database, Navigating databases, Information retrieval Systems, Sequence database Nucleotide(primary and Secondary), Protein sequence, Structure Databases: File Formats, Protein Structure, PDB, MMDB, CATH, Other Database Enzyme, MEROPS, BRENDA, Pathway databases
Unit III: Bioinformatics Tools: Need for tools, Industry Trends, Data Mining Tools, Data Submission tools: Nucleotide Sequence, protein Submission tools, Data Analysis tools: Nucleotide Sequence, protein Sequence, Prediction Tools: Phylogenetic trees, Gene prediction, Protein Structure and Function prediction, Modeling Tools: 2D and 3D Protein Modeling.
Unit IV: Bioinformatics Algorithms: Classification of Algorithms, Biological Algorithm, Sequence Comparison Algorithm, Substitution Matrices Algorithms, Sequence Alignment Algorithm ,Gene Prediction Algorithm.
Unit V: Bioinformatics Software: Local Alignment Search Tool (BLAST),Purpose of BLAST,BLAST Analysis, Purpose of BLAST II, Scoring Metrics, PAM, BLOSUM, Working of BLAST. Introduction of HMMER, Practical example of HMMER.
References:-
Orpita Bosu and Simminder Kaur Thukral, ”Bioinformatics Databases,Tools and Algorithms”, Oxford University Press 2007.
Harshawardhan P.bal, “Bioinformatics Principle and Applications”, TMH.
Lesk, A.M.2002, “Introduction to Bioinformatics”, Oxford University Press.
Rastogi, S.C. ,Mendiratta N, “Bioinformatics Concepts,Skill & Applications”, CBS Publishers.
Claverie, J.M and Notredame C, “Bioinformatics for Dummies”, Wiley Editior.
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