7th Semester CM 701 (C) Pharmaceutical Technology Syllabus RGPV / RGTU B.E. Chemical Engineering(CM) VII-7th Semester Syllabus

CM 701 (C) Pharmaceutical Technology  Syllabus
Chemical Engineering(CM) VII-7th Semester Syllabus

CM 701 (C) Pharmaceutical Technology Course Contents:

Unit I Practice of the following unit operation in pharmaceutical industries: Heat transfer, evaporation, distillation, drying, mixing, size reduction, crystallization, filtration, size separation, conveying, humidification, air conditioning and refrigeration.

Unit II Formulation, development of sterile dosage forms. Production facilities, environmental control and personnel in the production of sterile dosage form, compounding, processing, filtration, sealing, sterilization, packing and labeling of sterile dosage forms. Quality control tests like sterility, pyrogen, clarify, safety and leakage testing.

Unit III Types of tablets. Manufacturing of tablets by wet granulation, dry granulation and direct compression. Tablet processing problems and defects, tablet standardization: hardness, friability, weights variation, disintegration, dissolution and content uniformity tests.

Unit IV Capsules: Hard gelatin capsule, capsule size, formulation and preparation of filled hard gelatin capsules, soft gelatin capsule, soft gel - manufacturing procedures; quality control of capsules.

Unit V Cosmetics and Toiletries: Introduction, factors to be considered in the formulation of facial cosmetics, dentifrices, deodorant, antiperspirants, shampoos, hairdressing and hair removers.

Unit VI Pharmaceutical packing: packing components, types ofpacking containers and closures, materials used for and their pharmaceutical specification, method of evaluation, stability aspects of packaging materials.

1. Leon lachman, Lieberman; Theory & practice of industrial pharmacy; Verghese P, Mumbai
2. Ganderto; Unit process in pharmacy.
3. HersheyD; Chemical engineering in medicine and biology - Plenum press, new york.
4. Chemical engineering in medicine - chern. Engg. Progrer syrnp series no. C 66, vol 62.

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