RGPV / RGTU B Pharma, PHARMACY 3rd (III) Semester PY 303 APHARMACEUTICAL CHEMISTRY IV (ORGANIC CHEMISTRY II) syllabus (Theory)
BRANCH: BPharma, PHARMACY THIRD III SEMESTER
PY 303 PHARMACEUTICAL CHEMISTRY IV (ORGANIC CHEMISTRY II) (Theory)
(Modified on 25th September 2009)
2. Heterocyclic Chemistry: Nomenclature of Heterocycles: Nomenclature (Hantzsch-Widman system) for monocyclic (three, four, five, six and large membered), fused and bridged heterocycles. Aromatic and Non-aromatic Heterocycles: General chemical behaviour of aromatic heterocycles, classification (structural type), Heteroaromatic reactivity and tautomerism in aromatic heterocycles, Strain–bond angle and torsional strains and their consequences in small ring heterocycles Synthesis, chemical reactivity and medicinal application of the following heterocycles Three and four-membered heterocycles: Aziridines and azetidines Five membered hetero cycles: Furan, thiophen, pyrrole, pyrazole, oxazole, imidazole, triazole. Benzo-Fused Five-Membered Heterocycles: Benzimidazole, benzthiazole and benztriazole. Six-Membered Heterocycles with One, Two or More Heteroatoms: Pyridine and Pyrimidine. Fused heterocycles: Quinoline, isoquinoline, acridine, coumarins.
3. Organic Compounds with functional group containing nitrogen Structure, nomenclature of nitro and cyano compounds. Nitro compounds: Important methods of preparation, physical properties and chemical reactions. Cyanides and isocyanides: preparation, physical properties and chemical reactions.
4. Structure, Nomenclature and reactivity of Sulphur containing compounds