RGPV / RGTU B Pharma, PHARMACY 2nd (II) Semester PY 202 Pharmaceutics-II (Pharmaceutical Engineering-I) syllabus (Practicals)

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Rajiv Gandhi Technological University, Bhopal (MP)
BRANCH: BPharma, PHARMACY SECOND II SEMESTER
PY 202 Pharmaceutics-II (Pharmaceutical Engineering-I) (Practicals)
(Modified On 25th September 2009)

Related: Pharmaceutics-II (Pharmaceutical Engineering-I) (Theory) Syllabus

(Minimum fifteen experiments should be performed in the semester. Student should aware with safety parameters and handling of chemicals related to following experiments)

1. Determine the particle size and particle size distribution in the given sample of powder by optical microscopy.
2. Determine particle size distribution of the given granules by sieving method.
3. Determine the following derived properties of the given powdered sample
(a) Flow property (b) Bulk density (c) Granule density
(d) True density (e) Porosity (f) Carr’s Index
(g) hussnor’s retio
4. Determine the surface tension of the given sample by drop count and drop weight Method.
5. Determine the Critical Micelle Concentration (CMC) of the given surfactant by Surface tension method.
6. Determine partition coefficient of the given drug between benzene and water or octanol and
water system
7. Plot phase diagram of phenol-water system
8. Determine the effect of salt on the solubility of given drug.
9. Determine the percent composition of an unknown solution of glycerin in water using Ostwald’s viscometer
10. Study the effect of shear rate on the flow of 1% methyl cellulose solution.
11. Formulate suspension of the given drug and evaluate it for sedimentation parameters.
12. Study the effect of thickening agent concentration on the sedimentation of the suspension of the given drug.
13. Prepare acetate buffer and compare theoretical pH value with the experimental value.
14. Determine the viscosity of the following Newtonian and Non-Newtonian system
(a) Water (b) Simple syrup I.P.
(c) Diclofenac gel (d) Tooth paste
15. Determine the HLB value of the given surfactant
16. Evaluate the given sample of emulsion on the following parameters
(a) Type of emulsion (b) Globule size distribution
(c) Physical stability (d) Viscosity
17. Determine the optimum concentration of Bentonite required for the maximum physical stability of calamine lotion.
18. To observe the effect of hydrotropic agent sodium citrate on the solubility of salicylic acid. Experienced based on theory.

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